1HQM
CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION
Replaces: 1DDQEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA-directed RNA polymerase subunit alpha | polymer | 313 | 34955.0 | 2 | UniProt (Q9KWU8) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) | Thermus aquaticus | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C (C) | DNA-directed RNA polymerase subunit beta | polymer | 1119 | 124930.1 | 1 | UniProt (Q9KWU7) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) | Thermus aquaticus | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D (D) | DNA-directed RNA polymerase subunit beta' | polymer | 1265 | 141365.5 | 1 | UniProt (Q9KWU6) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) | Thermus aquaticus | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E (E) | DNA-directed RNA polymerase subunit omega | polymer | 99 | 11642.4 | 1 | UniProt (Q9EVV4) Pfam (PF01192) | Thermus aquaticus | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | F (D) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | G (D) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A, B: 1 - 313 (UniProt: Q9KWU8)
C: 1 - 1119 (UniProt: Q9KWU7)
D: 1 - 155 (UniProt: Q9KWU6)
D: 2 - 46 (PDB: 1HQM)
D: 452 - 1525 (UniProt: Q9KWU6)
| PDB | External Database | Details |
|---|---|---|
| - | Lys 93 | deletion |
| Arg 93 | Met 94 | conflict |
| Trp 94 | Ala 95 | conflict |
| Arg 95 | Ser 96 | conflict |
| Val 111 | Gly 112 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Lys 2 | Glu 2 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Phe 119 | Ser 119 | conflict |
D: 452 - 1525 (UniProt: Q9KWU6)
| PDB | External Database | Details |
|---|---|---|
| Thr 863 | Val 863 | conflict |
| Thr 866 | Val 866 | conflict |
| Asn 876 | Ser 876 | conflict |
| Ile 947 | - | insertion |
| Asn 1010 | Lys 1009 | conflict |
| Lys 1117 | Asn 1116 | conflict |
| Pro 1389 | Arg 1388 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 347848.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 89.7 | |
| All* | Total formula weight | 347937.8 |
