1HPV
CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH VX-478, A POTENT AND ORALLY BIOAVAILABLE INHIBITOR OF THE ENZYME
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 PROTEASE | polymer | 99 | 10803.8 | 2 | UniProt (P04587) | Human immunodeficiency virus 1 | |
| 2 | C (B) | {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER | non-polymer | 505.6 | 1 | Chemie (478) PubChem (2177) PubChem (22868212) PubChem (65016) PubChem (44342222) PubChem (59964701) PubChem (68088939) PubChem (68336859) PubChem (68164690) PubChem (441385) PubChem (92209736) PubChem (124638074) PubChem (10885665) PubChem (11168069) PubChem (6540587) PubChem (9898472) PubChem (141823677) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21607.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 505.6 | |
| All* | Total formula weight | 22113.1 |
