1HEF
The crystal structures at 2.2 angstroms resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | E | HIV-1 PROTEASE | polymer | 99 | 10786.7 | 1 | UniProt (P03366) Pfam (PF00077) In PDB | Human immunodeficiency virus 1 | |
| 2 | I | SKF 108738 PEPTIDE INHIBITOR | polymer | 5 | 667.8 | 1 | BIRD (PRD_000319) | ||
| 3 | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
E: 1 - 99 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Asn 36 | Met 104 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 11454.5 | |
| All* | Total formula weight | 11454.5 |
