1HE1
Crystal structure of the complex between the GAP domain of the Pseudomonas aeruginosa ExoS toxin and human Rac
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | EXOENZYME S | polymer | 135 | 14261.2 | 2 | UniProt (Q51451) Pfam (PF03545) | PSEUDOMONAS AERUGINOSA | EXOS |
| 2 | C, D (C, D) | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 | polymer | 176 | 19563.5 | 2 | UniProt (P15154) Pfam (PF00071) UniProt (by SIFTS) (P63000) | HOMO SAPIENS (HUMAN) | P21-RAC1, RAS-LIKE PROTEIN TC25 |
| 3 | E, I, J, N (A, C, D) | NICKEL (II) ION | non-polymer | 58.7 | 4 | Chemie (NI) | |||
| 4 | F, K (C, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 5 | G, L (C, D) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 2 | Chemie (AF3) | |||
| 6 | H, M (C, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 712 | Chemie (HOH) |
Sequence modifications
A, B: 95 - 229 (UniProt: Q51451)
C, D: 1 - 176 (UniProt: P15154)
| PDB | External Database | Details |
|---|---|---|
| Ala 95 | Met 1 | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Pro 1 | Met 1 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 67649.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1337.7 | |
| All* | Total formula weight | 68987.1 |
