1HE1
Crystal structure of the complex between the GAP domain of the Pseudomonas aeruginosa ExoS toxin and human Rac
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | EXOENZYME S | polymer | 135 | 14261.2 | 2 | UniProt (Q51451) | PSEUDOMONAS AERUGINOSA | EXOS |
| 2 | C, D (C, D) | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 | polymer | 176 | 19563.5 | 2 | UniProt (P15154) Pfam (PF00071) UniProt (by SIFTS) (P63000) | HOMO SAPIENS (HUMAN) | P21-RAC1, RAS-LIKE PROTEIN TC25 |
| 3 | E, I, J, N (A, C, D) | NICKEL (II) ION | non-polymer | 58.7 | 4 | Chemie (NI) PubChem (934) | |||
| 4 | F, K (C, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | G, L (C, D) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 2 | Chemie (AF3) PubChem (2124) | |||
| 6 | H, M (C, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 7 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 712 | Chemie (HOH) |
Sequence modifications
A, B: 95 - 229 (UniProt: Q51451)
C, D: 1 - 176 (UniProt: P15154)
| PDB | External Database | Details |
|---|---|---|
| Ala 95 | Met 1 | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Pro 1 | Met 1 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 67649.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1337.7 | |
| All* | Total formula weight | 68987.1 |
