1HDC
MECHANISM OF INHIBITION OF 3ALPHA,20BETA-HYDROXYSTEROID DEHYDROGENASE BY A LICORICE-DERIVED STEROIDAL INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3-ALPHA, 20 BETA-HYDROXYSTEROID DEHYDROGENASE | polymer | 254 | 26390.7 | 4 | UniProt (P19992) Pfam (PF00106) | Streptomyces exfoliatus | |
| 2 | E, F, G, H (A, B, C, D) | CARBENOXOLONE | non-polymer | 570.8 | 4 | Chemie (CBO) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 255 (UniProt: P19992)
| PDB | External Database | Details |
|---|---|---|
| Glu 109 | Asp 109 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 105562.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2283.0 | |
| All* | Total formula weight | 107845.8 |
