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1HBT

Human alpha-thrombin complexed with a peptidyl pyridinium methyl ketone containing bivalent inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
ALPHA-THROMBIN (SMALL SUBUNIT)polymer364096.51UniProt (P00734)
Pfam (PF09396)
Homo sapiens (human)Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain
2B
(H)
ALPHA-THROMBIN (LARGE SUBUNIT)polymer25929780.21UniProt (P00734)
Pfam (PF00089)
Homo sapiens (human)Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain
3C
(I)
P596 Inhibitor peptidepolymer182116.31
4D, E, F
(L, H, I)
waterwater18.0185Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight35993.1
All*Total formula weight35993.1
*Water molecules are not included.

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PDB entries from 2025-12-24

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