1H8D
X-ray structure of the human alpha-thrombin complex with a tripeptide phosphonate inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | THROMBIN | polymer | 260 | 29797.4 | 1 | UniProt (P00734) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II |
| 2 | B (I) | HIRUDIN I | polymer | 10 | 1363.4 | 1 | UniProt (P01050) | HIRUDO MEDICINALIS (MEDICINAL LEECH) | LEPIRUDIN |
| 3 | C (L) | THROMBIN | polymer | 29 | 3404.8 | 1 | UniProt (P00734) Pfam (PF09396) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II |
| 4 | D (H) | N-[(benzyloxy)carbonyl]-beta-phenyl-D-phenylalanyl-N-{(1S,3E)-1-[dihydroxy(diphenoxy)-lambda~5~-phosphanyl]-4-methoxybut-3-en-1-yl}-L-prolinamide | non-polymer | 805.9 | 1 | Chemie (PHW) | |||
| 5 | E, F, G (H, I, L) | water | water | 18.0 | 684 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34565.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 805.9 | |
| All* | Total formula weight | 35371.5 |
