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1H1R

Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6086

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CCELL DIVISION PROTEIN KINASE 2polymer30334467.92UniProt (P24941)
Pfam (PF00069)
In PDB
HOMO SAPIENS (HUMAN)CYCLIN-DEPENDENT KINASE 2, P33 PROTEIN KINASE
2B, DCYCLIN A2polymer25829624.32UniProt (P20248)
Pfam (PF00134)
Pfam (PF02984)
In PDB
HOMO SAPIENS (HUMAN)CYCLIN A, CYCLIN A3
3A, C6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINEnon-polymer357.82Chemie (6CP)
4waterwater18.0723Chemie (HOH)
Sequence modifications
A, C: -4 - 0 (PDB: 1H1R)
A, C: 1 - 298 (UniProt: P24941)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight128184.4
Non-Polymers*Number of molecules2
Total formula weight715.7
All*Total formula weight128900.1
*Water molecules are not included.

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PDB entries from 2024-03-27

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