1GZH
Crystal structure of the BRCT domains of human 53BP1 bound to the p53 tumor supressor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | CELLULAR TUMOR ANTIGEN P53 | polymer | 198 | 22375.5 | 1 | UniProt (P04637) Pfam (PF00870) In PDB | HOMO SAPIENS (HUMAN) | TUMOR SUPPRESSOR P53, PHOSPHOPROTEIN P53, ANTIGEN NY-CO-13 |
| 2 | B, D | TUMOR SUPPRESSOR P53-BINDING PROTEIN 1 | polymer | 249 | 28175.9 | 2 | UniProt (Q12888) Pfam (PF18428) In PDB | HOMO SAPIENS (HUMAN) | P53-BINDING PROTEIN 1,53BP1 |
| 3 | C | CELLULAR TUMOR ANTIGEN P53 | polymer | 198 | 22361.5 | 1 | UniProt (P04637) Pfam (PF00870) In PDB | HOMO SAPIENS (HUMAN) | TUMOR SUPPRESSOR P53, PHOSPHOPROTEIN P53, ANTIGEN NY-CO-13 |
| 4 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | B, D | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A: 95 - 292 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Glu 228 | Asp 228 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 101088.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 322.9 | |
| All* | Total formula weight | 101411.7 |
