1GW6
STRUCTURE OF LEUKOTRIENE A4 HYDROLASE D375N MUTANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | LEUKOTRIENE A-4 HYDROLASE | polymer | 610 | 69231.8 | 1 | UniProt (P09960) Pfam (PF17900) Pfam (PF01433) Pfam (PF09127) | HOMO SAPIENS (HUMAN) | LTA-4 HYDROLASE, LEUKOTRIENE A(4)HYDROLASE, LTA-4 HYDROLASE, LEUKOTRIENE A(4) HYDROLASE |
| 2 | B (A) | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID | non-polymer | 308.4 | 1 | Chemie (BES) | |||
| 3 | C (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | D (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 5 | E (A) | YTTERBIUM (III) ION | non-polymer | 173.0 | 1 | Chemie (YB) | |||
| 6 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | G (A) | water | water | 18.0 | 440 | Chemie (HOH) |
Sequence modifications
A: 1 - 610 (UniProt: P09960)
| PDB | External Database | Details |
|---|---|---|
| Asn 375 | Asp 375 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 69231.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 675.0 | |
| All* | Total formula weight | 69906.7 |
