1GT0
Crystal structure of a POU/HMG/DNA ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*TP*TP* GP*GP*AP* TP*GP*CP*TP*AP*AP*TP*GP*GP*GP*A)-3' | polymer | 24 | 7436.8 | 1 | MUS MUSCULUS | ||
| 2 | B (B) | 5'-D(*AP*TP*CP*CP*CP*AP*TP*TP*AP*GP* CP*AP*TP*CP*CP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3' | polymer | 24 | 7299.8 | 1 | MUS MUSCULUS | ||
| 3 | C (C) | OCTAMER-BINDING TRANSCRIPTION FACTOR 1 | polymer | 159 | 18327.8 | 1 | UniProt (P14859) Pfam (PF00157) Pfam (PF00046) | HOMO SAPIENS (HUMAN) | OTF-1, NF-A1, OCT-1 |
| 4 | D (D) | TRANSCRIPTION FACTOR SOX-2 | polymer | 80 | 9833.5 | 1 | UniProt (P48432) Pfam (PF00505) | MUS MUSCULUS (MOUSE) | |
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
C: 1 - 160 (UniProt: P14859)
| PDB | External Database | Details |
|---|---|---|
| Ser 61 | Cys 340 | engineered mutation |
| Ser 150 | Cys 428 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42897.9 | |
| All* | Total formula weight | 42897.9 |
