1GT0

Crystal structure of a POU/HMG/DNA ternary complex

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. IAdqLnMEkeVIRVWFsNrrqkeK

Chain	Residue	Details
C	ILE134-LYS157

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site_id	PS00035
Number of Residues	13
Details	POU_1 POU-specific (POUs) domain signature 1. RRIkLGFtQgDVG

Chain	Residue	Details
C	ARG19-GLY31

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site_id	PS00465
Number of Residues	14
Details	POU_2 POU-specific (POUs) domain signature 2. SQTTISRFEaLnLS

Chain	Residue	Details
C	SER43-SER56

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	68
Details	DNA_BIND: HMG box => ECO:0000255|PROSITE-ProRule:PRU00267

Chain	Residue	Details
D	VAL3-LYS71

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-methyllysine => ECO:0000250|UniProtKB:P48431

Chain	Residue	Details
D	LYS4
D	LYS79

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:1684878

Chain	Residue	Details
C	SER107

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