1GSZ
Crystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C (A, B, C) | SQUALENE--HOPENE CYCLASE | polymer | 631 | 71650.0 | 3 | UniProt (P33247) Pfam (PF00432) Pfam (PF13243) | ALICYCLOBACILLUS ACIDOCALDARIUS | |
2 | D, F, H (A, B, C) | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE | non-polymer | 306.4 | 3 | Chemie (C8E) | |||
3 | E, G, I (A, B, C) | [4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE | non-polymer | 448.4 | 3 | Chemie (R71) | |||
4 | J, K, L (A, B, C) | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 214950.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2264.4 | |
All* | Total formula weight | 217214.5 |