1GPO
CRYSTAL STRUCTURE OF THE RATIONALLY DESIGNED ANTIBODY M41 AS A FAB FRAGMENT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (L, M) | ANTIBODY M41 | polymer | 219 | 24172.5 | 2 | UniProt (P01837) Pfam (PF07654) | Mus musculus (mouse) | |
| 2 | B, D (H, I) | ANTIBODY M41 | polymer | 221 | 24182.8 | 2 | EMBL (AJ303449) Pfam (PF07654) UniProt (by SIFTS) (P01868) | Mus musculus (mouse) | |
| 3 | E, F (H, I) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | G, H, I, J (L, H, M, I) | water | water | 18.0 | 649 | Chemie (HOH) |
Sequence modifications
H, I: 1 - 215 (EMBL: AJ303449)
| PDB | External Database | Details |
|---|---|---|
| Lys 3 | Gln 3 | conflict |
| Asp 32 | Gly 32 | conflict |
| Phe 33 | Tyr 33 | conflict |
| Ser 35 | Asn 35 | conflict |
| Gln 39 | Lys 39 | conflict |
| Arg 44 | Lys 44 | conflict |
| Phe 50 | Tyr 50 | conflict |
| Val 51 | Ile 51 | conflict |
| Gln 52 | Ser 52 | conflict |
| Ser 54 | Gly 54 | conflict |
| Glu 56 | Ser 56 | conflict |
| Ala 58 | Tyr 58 | conflict |
| Lys 64 | Glu 64 | conflict |
| Asp 81 | Gln 81 | conflict |
| Val 92 | Thr 92 | conflict |
| Tyr 94 | Phe 94 | conflict |
| Asn 97 | Arg 97 | conflict |
| Trp 98 | Leu 98 | conflict |
| His 99 | Phe 99 | conflict |
| - | Ser 101 | deletion |
| - | Tyr 102 | deletion |
| - | Tyr 103 | deletion |
| - | Phe 104 | deletion |
| Val 109 | Leu 113 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 96710.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 96902.8 |
