1GPO

CRYSTAL STRUCTURE OF THE RATIONALLY DESIGNED ANTIBODY M41 AS A FAB FRAGMENT

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0005515	molecular_function	protein binding
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0030183	biological_process	B cell differentiation
L	0042105	cellular_component	alpha-beta T cell receptor complex
L	0071735	cellular_component	IgG immunoglobulin complex
M	0002250	biological_process	adaptive immune response
M	0005515	molecular_function	protein binding
M	0005576	cellular_component	extracellular region
M	0005886	cellular_component	plasma membrane
M	0030183	biological_process	B cell differentiation
M	0042105	cellular_component	alpha-beta T cell receptor complex
M	0071735	cellular_component	IgG immunoglobulin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 650

Chain	Residue
H	VAL51
H	GLY55
H	THR70
H	ARG71
H	HOH705

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 I 651

Chain	Residue
I	HOH527
I	VAL51
I	GLY55
I	THR70
I	ARG71

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR197-HIS203

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	194
Details	Domain: {"description":"Ig-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	192
Details	Region: {"description":"CH1"}

Chain

Residue

Details

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