1GO4
Crystal structure of Mad1-Mad2 reveals a conserved Mad2 binding motif in Mad1 and Cdc20.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Mitotic spindle assembly checkpoint protein MAD2A | polymer | 205 | 23447.8 | 4 | UniProt (Q13257) Pfam (PF02301) | Homo sapiens (Human) | HsMAD2,Mitotic arrest deficient 2-like protein 1,MAD2-like protein 1 |
| 2 | E, F, G, H (E, F, G, H) | Mitotic spindle assembly checkpoint protein MAD1 | polymer | 100 | 11693.1 | 4 | UniProt (Q9Y6D9) | Homo sapiens (Human) | Mitotic arrest deficient 1-like protein 1,MAD1-like protein 1,Mitotic checkpoint MAD1 protein homolog,hMAD1,Tax-binding protein 181 |
| 3 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 628 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 205 (UniProt: Q13257)
| PDB | External Database | Details |
|---|---|---|
| Ala 133 | Arg 133 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 140563.5 | |
| All* | Total formula weight | 140563.5 |
