1GJA
ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | UROKINASE-TYPE PLASMINOGEN ACTIVATOR | polymer | 23 | 2708.2 | 1 | UniProt (P00749) In PDB | Homo sapiens (human) | UPA, U-PLASMINOGEN ACTIVATOR, UROKINASE-PLASMINOGEN ACTIVATOR |
2 | B | UROKINASE-TYPE PLASMINOGEN ACTIVATOR | polymer | 253 | 28435.4 | 1 | UniProt (P00749) Pfam (PF00089) In PDB | Homo sapiens (human) | UPA, U-PLASMINOGEN ACTIVATOR, UROKINASE-PLASMINOGEN ACTIVATOR |
3 | B | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
4 | B | N-(4-CARBAMIMIDOYL-PHENYL)-2-HYDROXY-BENZAMIDE | non-polymer | 255.3 | 1 | Chemie (135) | |||
5 | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
B: 16 - 250 (UniProt: P00749)
PDB | External Database | Details |
---|---|---|
Ala 145 | Asn 322 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31143.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 639.5 | |
All* | Total formula weight | 31783.1 |