1G9N
HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | ENVELOPE GLYCOPROTEIN GP120 | polymer | 313 | 34838.7 | 1 | UniProt (P35961) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 2 | B (C) | T-CELL SURFACE GLYCOPROTEIN CD4 | polymer | 185 | 20503.3 | 1 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) | Homo sapiens (human) | |
| 3 | C (L) | ANTIBODY 17B, LIGHT CHAIN | polymer | 214 | 23440.0 | 1 | Homo sapiens (human) | ||
| 4 | D (H) | ANTIBODY 17B, HEAVY CHAIN | polymer | 229 | 24525.6 | 1 | Homo sapiens (human) | ||
| 5 | E, F, G, H, I... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 14 | Chemie (NAG) | |||
| 6 | S, T, U, V (G, C, L, H) | water | water | 18.0 | 345 | Chemie (HOH) |
Sequence modifications
G: 83 - 127 (UniProt: P35961)
G: 195 - 297 (UniProt: P35961)
G: 330 - 492 (UniProt: P35961)
C: 1 - 185 (UniProt: P01730)
| PDB | External Database | Details |
|---|---|---|
| Gly 79 | - | cloning artifact |
| Ala 80 | - | cloning artifact |
| Arg 81 | - | cloning artifact |
| Ser 82 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 128 | - | see remark 999 |
| Ala 129 | - | see remark 999 |
| Gly 194 | - | see remark 999 |
| PDB | External Database | Details |
|---|---|---|
| Gly 298 | - | see remark 999 |
| Ala 299 | - | see remark 999 |
| Gly 329 | - | see remark 999 |
| PDB | External Database | Details |
|---|---|---|
| Asn 184 | Ser 209 | engineered mutation |
| Thr 185 | Ile 210 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 103307.5 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3096.9 | |
| All* | Total formula weight | 106404.4 |
