1G73
CRYSTAL STRUCTURE OF SMAC BOUND TO XIAP-BIR3 DOMAIN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | SECOND MITOCHONDRIA-DERIVED ACTIVATOR OF CASPASES | polymer | 162 | 18115.3 | 2 | UniProt (Q9NR28) Pfam (PF09057) In PDB | Homo sapiens (human) | SMAC/DIABLO |
| 2 | C, D | INHIBITORS OF APOPTOSIS-LIKE PROTEIN ILP | polymer | 121 | 13925.4 | 2 | UniProt (P98170) Pfam (PF00653) In PDB | Homo sapiens (human) | IAP-LIKE PROTEIN ILP |
| 3 | B, D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, B: 1 - 162 (UniProt: Q9NR28)
| PDB | External Database | Details |
|---|---|---|
| Asp 33 | Phe 88 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 64081.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 64212.4 |
