1G3N
STRUCTURE OF A P18(INK4C)-CDK6-K-CYCLIN TERNARY COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, E) | CYCLIN-DEPENDENT KINASE 6 | polymer | 326 | 36987.3 | 2 | UniProt (Q00534) Pfam (PF00069) | Homo sapiens (human) | CELL DIVISION PROTEIN KINASE 6, PROTEIN KINASE CDK6 |
| 2 | B, E (B, F) | CYCLIN-DEPENDENT KINASE 6 INHIBITOR | polymer | 168 | 18149.4 | 2 | UniProt (P42773) Pfam (PF12796) | Homo sapiens (human) | P18(INK4C), CYCLIN-DEPENDENT KINASE INHIBITOR 2C, P18, INHIBITS CDK4, CYCLIN-DEPENDENT KINASE 4 INHIBITOR C, P18-INK4C |
| 3 | C, F (C, G) | V-CYCLIN | polymer | 257 | 28094.3 | 2 | UniProt (O40946) Pfam (PF00134) Pfam (PF09080) UniProt (by SIFTS) (Q98147) | Human herpesvirus 8 | K-CYCLIN, FUNCTIONAL CYCLIN D HOMOLOG |
Sequence modifications
C, G: 1 - 257 (UniProt: O40946)
| PDB | External Database | Details |
|---|---|---|
| Val 163 | Leu 163 | conflict |
| Leu 188 | Lys 188 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 166461.9 | |
| All* | Total formula weight | 166461.9 |
