1FWM
Crystal structure of the thymidylate synthase R166Q mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | THYMIDYLATE SYNTHASE | polymer | 264 | 30530.6 | 2 | UniProt (P0A884) Pfam (PF00303) In PDB | Escherichia coli | |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | A, B | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID | non-polymer | 477.5 | 2 | Chemie (CB3) | |||
| 4 | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 264 (UniProt: P0A884)
| PDB | External Database | Details |
|---|---|---|
| Cxm 1 | Met 1 | modified residue |
| Gln 166 | Arg 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61061.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1147.1 | |
| All* | Total formula weight | 62208.3 |
