1FS1
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | CYCLIN A/CDK2-ASSOCIATED P19 | polymer | 53 | 6105.0 | 2 | UniProt (Q13309) Pfam (PF12937) | Homo sapiens (human) | SKP2 F-BOX |
| 2 | B, D (B, D) | CYCLIN A/CDK2-ASSOCIATED P45 | polymer | 141 | 16013.3 | 2 | UniProt (P63208) Pfam (PF03931) Pfam (PF01466) | Homo sapiens (human) | SKP1 |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 570 | Chemie (HOH) |
Sequence modifications
B, D: 1 - 147 (UniProt: P63208)
| PDB | External Database | Details |
|---|---|---|
| - | Asp 37 | deletion |
| - | Asp 38 | deletion |
| - | Glu 39 | deletion |
| - | Gly 40 | deletion |
| - | Asp 41 | deletion |
| - | Asp 42 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44236.6 | |
| All* | Total formula weight | 44236.6 |
