1FRG
CRYSTAL STRUCTURE, SEQUENCE, AND EPITOPE MAPPING OF A PEPTIDE COMPLEX OF AN ANTI-INFLUENZA HA PEPTIDE ANTIBODY FAB 26(SLASH)9: FINE-TUNING ANTIBODY SPECIFICITY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | IGG2A 26/9 FAB (LIGHT CHAIN) | polymer | 217 | 24028.7 | 1 | PIR (A31790) Pfam (PF07654) UniProt (by SIFTS) (P01837) | Mus musculus (mouse) | |
| 2 | B (H) | IGG2A 26/9 FAB (HEAVY CHAIN) | polymer | 220 | 23756.7 | 1 | GenBank (533229) Pfam (PF07654) UniProt (by SIFTS) (P01864) | Mus musculus (mouse) | |
| 3 | C (P) | INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 101 - 108) | polymer | 10 | 903.0 | 1 | UniProt (by SIFTS) (E3W6A8) | ||
| 4 | D (L) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
L: 1 - 217 (PIR: A31790)
H: 218 - 437 (GenBank: 533229)
| PDB | External Database | Details |
|---|---|---|
| Lys 24 | Thr 24 | conflict |
| Arg 35 | Gln 35 | conflict |
| Phe 38 | Tyr 38 | conflict |
| His 43 | Gln 43 | conflict |
| Leu 52 | Val 52 | conflict |
| Ser 69 | Thr 69 | conflict |
| Thr 82 | Ser 82 | conflict |
| Ile 91 | Val 91 | conflict |
| His 100 | Asn 100 | conflict |
| Ala 106 | Gly 106 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Leu 220 | Gln 3 | conflict |
| Phe 234 | Ser 17 | conflict |
| Thr 245 | Ser 28 | conflict |
| Phe 249 | Tyr 32 | conflict |
| His 256 | Gln 39 | conflict |
| Gln 278 | Pro 61 | conflict |
| Phe 297 | Tyr 80 | conflict |
| Glu 299 | Gln 82 | conflict |
| Thr 301 | Ser 84 | conflict |
| Ala 308 | Ser 91 | conflict |
| Gly 309 | Ala 92 | conflict |
| Leu 310 | Met 93 | conflict |
| Lys 322 | Asn 105 | conflict |
| Arg 329 | Gln 112 | conflict |
| Pro 436 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48688.3 | |
| All* | Total formula weight | 48688.3 |
