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1FM9

THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RETINOIC ACID RECEPTOR RXR-ALPHApolymer23826667.91UniProt (P19793)
Pfam (PF00104)
Homo sapiens (human)
2B
(D)
PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMApolymer27231094.11UniProt (P37231)
Pfam (PF00104)
Homo sapiens (human)
3C, D
(B, E)
STEROID RECEPTOR COACTIVATORpolymer252806.22UniProt (O43793)
Pfam (PF08832)
UniProt (by SIFTS) (Q15788)
4E
(A)
(9cis)-retinoic acidnon-polymer300.41Chemie (9CR)
5F
(D)
2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACIDnon-polymer546.61Chemie (570)
6G, H, I
(A, D, E)
waterwater18.0131Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight63374.3
Non-Polymers*Number of molecules2
Total formula weight847.0
All*Total formula weight64221.4
*Water molecules are not included.

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