1FM9
THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | RETINOIC ACID RECEPTOR RXR-ALPHA | polymer | 238 | 26667.9 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | |
2 | B (D) | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA | polymer | 272 | 31094.1 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | |
3 | C, D (B, E) | STEROID RECEPTOR COACTIVATOR | polymer | 25 | 2806.2 | 2 | UniProt (O43793) Pfam (PF08832) UniProt (by SIFTS) (Q15788) | ||
4 | E (A) | (9cis)-retinoic acid | non-polymer | 300.4 | 1 | Chemie (9CR) | |||
5 | F (D) | 2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID | non-polymer | 546.6 | 1 | Chemie (570) | |||
6 | G, H, I (A, D, E) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 63374.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 847.0 | |
All* | Total formula weight | 64221.4 |