1FM6
THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, U) | RETINOIC ACID RECEPTOR RXR-ALPHA | polymer | 238 | 26667.9 | 2 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | |
| 2 | B, D (D, X) | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA | polymer | 272 | 31094.1 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | |
| 3 | E, F, G, H (B, V, E, Y) | STEROID RECEPTOR COACTIVATOR | polymer | 25 | 2806.2 | 4 | UniProt (O43793) Pfam (PF08832) UniProt (by SIFTS) (Q15788) | ||
| 4 | I, K (A, U) | (9cis)-retinoic acid | non-polymer | 300.4 | 2 | Chemie (9CR) | |||
| 5 | J, L (D, X) | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL) | non-polymer | 357.4 | 2 | Chemie (BRL) | |||
| 6 | M, N, O, P, Q... (A, D, U, X, B...) | water | water | 18.0 | 452 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 126748.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1315.7 | |
| All* | Total formula weight | 128064.4 |
