1FHX
Structure of the pleckstrin homology domain from GRP1 in complex with inositol 1,3,4,5-tetrakisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1 | polymer | 129 | 15360.1 | 2 | UniProt (O08967) Pfam (PF00169) | Mus musculus (house mouse) | GRP1 |
| 2 | C, F (A, B) | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE | non-polymer | 500.1 | 2 | Chemie (4IP) | |||
| 3 | D, E (B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B: 264 - 391 (UniProt: O08967)
| PDB | External Database | Details |
|---|---|---|
| Mse 263 | - | cloning artifact |
| Mse 372 | Met 372 | modified residue |
| Mse 387 | Met 387 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30720.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1192.3 | |
| All* | Total formula weight | 31912.5 |
