1FDV
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 MUTANT H221L COMPLEXED WITH NAD+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | 17-BETA-HYDROXYSTEROID DEHYDROGENASE | polymer | 327 | 34949.0 | 4 | UniProt (P14061) Pfam (PF00106) In PDB | Homo sapiens (human) | |
| 2 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | A, B, C, D | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 4 | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 327 (UniProt: P14061)
| PDB | External Database | Details |
|---|---|---|
| Leu 221 | His 221 | engineered mutation |
| Arg 301 | Ala 301 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 139795.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3038.0 | |
| All* | Total formula weight | 142833.8 |
