1FAK
HUMAN TISSUE FACTOR COMPLEXED WITH COAGULATION FACTOR VIIA INHIBITED WITH A BPTI-MUTANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | PROTEIN (BLOOD COAGULATION FACTOR VIIA) | polymer | 152 | 17487.1 | 1 | UniProt (P08709) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | |
| 2 | B (H) | PROTEIN (BLOOD COAGULATION FACTOR VIIA) | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (T) | PROTEIN (SOLUBLE TISSUE FACTOR) | polymer | 206 | 23417.1 | 1 | UniProt (P13726) Pfam (PF01108) Pfam (PF09294) | Homo sapiens (human) | |
| 4 | D (I) | PROTEIN (5L15) | polymer | 55 | 6299.2 | 1 | UniProt (P00974) Pfam (PF00014) | ||
| 5 | E (L) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 6 | F (L) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 7 | G, H (L, H) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 8 | I, J, K, L (L, H, T, I) | water | water | 18.0 | 340 | Chemie (HOH) |
Sequence modifications
I: 1 - 55 (UniProt: P00974)
| PDB | External Database | Details |
|---|---|---|
| Asp 11 | Thr 46 | conflict |
| Arg 15 | Lys 50 | conflict |
| Leu 17 | Arg 52 | conflict |
| His 18 | Ile 53 | conflict |
| Leu 19 | Ile 54 | conflict |
| Tyr 34 | Val 69 | conflict |
| Leu 39 | Arg 74 | conflict |
| Glu 46 | Lys 81 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 75306.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 424.5 | |
| All* | Total formula weight | 75731.0 |
