1F8C
Native Influenza Neuraminidase in Complex with 4-amino-2-deoxy-2,3-dehydro-N-neuraminic Acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NEURAMINIDASE | polymer | 388 | 43723.8 | 1 | GenBank (324880) Pfam (PF00064) UniProt (by SIFTS) (P03472) In PDB | Influenza A virus (A/tern/Australia/G70C/1975(H11N9)) | |
| 2 | B | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G57082ZE) | |||
| 3 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | A | 4-AMINO-2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID | non-polymer | 290.3 | 1 | Chemie (4AM) | |||
| 7 | water | water | 18.0 | 367 | Chemie (HOH) |
Sequence modifications
A: 82 - 468 (GenBank: 324880)
| PDB | External Database | Details |
|---|---|---|
| Met 376 | Ile 377 | conflict |
| Asp 386 | Glu 387 | conflict |
| Lys 387 | Arg 388 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43723.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1659.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 591.6 | |
| All* | Total formula weight | 45974.9 |
