1F66

2.6 A CRYSTAL STRUCTURE OF A NUCLEOSOME CORE PARTICLE CONTAINING THE VARIANT HISTONE H2A.Z

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	I, J	PALINDROMIC 146 BASE PAIR DNA FRAGMENT	polymer	146	45054.8	2
2	A, E	HISTONE H3	polymer	136	15507.2	2	UniProt (Q7ZT64) Pfam (PF00125) UniProt (by SIFTS) (P84233) In PDB	Xenopus laevis (African clawed frog)
3	B, F	HISTONE H4	polymer	103	11394.4	2	UniProt (P62806) Pfam (PF15511) In PDB	Mus musculus (house mouse)
4	C, G	HISTONE H2A.Z	polymer	128	13581.8	2	UniProt (P17317) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P0C0S5) In PDB	Homo sapiens (human)
5	D, H	HISTONE H2B	polymer	126	13979.3	2	UniProt (P02281) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)
6	I, J, C, E, G	MANGANESE (II) ION	non-polymer		54.9	15	Chemie (MN)
7		water	water		18.0	325	Chemie (HOH)

Sequence modifications

A, E: 400 - 535 (UniProt: Q7ZT64)

PDB	External Database	Details
Glu 434	Gly 35	conflict
Val 517	Ile 118	conflict

D, H: 1198 - 1322 (UniProt: P02281)

PDB	External Database	Details
Thr 1229	Ser 32	conflict

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	199035.1
Non-Polymers*	Number of molecules	15
	Total formula weight	824.1
All*	Total formula weight	199859.2

*Water molecules are not included.