1F3F
STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE) | polymer | 155 | 16735.2 | 3 | UniProt (P22887) Pfam (PF00334) | Dictyostelium discoideum | NDP KINASE, NDK |
| 2 | D, G, J (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | E, H, K (A, B, C) | 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE | non-polymer | 464.2 | 3 | Chemie (D4T) | |||
| 4 | F (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | I (B) | 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-DIPHOSPHATE | non-polymer | 384.2 | 1 | Chemie (D4D) | |||
| 6 | L, M, N (A, B, C) | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 155 (UniProt: P22887)
| PDB | External Database | Details |
|---|---|---|
| Gly 122 | His 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50205.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1944.5 | |
| All* | Total formula weight | 52150.2 |
