1EX4
HIV-1 INTEGRASE CATALYTIC CORE AND C-TERMINAL DOMAIN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | INTEGRASE | polymer | 239 | 26427.0 | 2 | UniProt (P04585) Pfam (PF00665) Pfam (PF00552) | Human immunodeficiency virus 1 | |
| 2 | C, D, E, F (A, B) | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE | non-polymer | 614.9 | 4 | Chemie (CPS) | |||
| 3 | G, H (A, B) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence modifications
A, B: 52 - 288 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Gly 50 | - | cloning artifact |
| Ser 51 | - | cloning artifact |
| Ser 56 | Cys 57 | engineered mutation |
| Asp 131 | Trp 132 | engineered mutation |
| Asp 139 | Phe 140 | engineered mutation |
| Lys 185 | Phe 186 | engineered mutation |
| Ser 280 | Cys 281 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52854.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2459.5 | |
| All* | Total formula weight | 55313.5 |
