1EV2
CRYSTAL STRUCTURE OF FGF2 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 2 (FGFR2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | PROTEIN (FIBROBLAST GROWTH FACTOR 2) | polymer | 132 | 15110.3 | 4 | UniProt (P09038) Pfam (PF00167) | Homo sapiens (human) | FGF2 |
| 2 | E, F, G, H (E, F, G, H) | PROTEIN (FIBROBLAST GROWTH FACTOR RECEPTOR 2) | polymer | 220 | 24640.9 | 4 | UniProt (P21802) Pfam (PF07679) Pfam (PF13927) | Homo sapiens (human) | FGFR2 |
| 3 | I, J, K, L (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 15 - 146 (UniProt: P09038)
| PDB | External Database | Details |
|---|---|---|
| Ser 69 | Cys 78 | engineered mutation |
| Ser 87 | Cys 96 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 159005.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 159389.3 |
