1ES0

CRYSTAL STRUCTURE OF THE MURINE CLASS II ALLELE I-A(G7) COMPLEXED WITH THE GLUTAMIC ACID DECARBOXYLASE (GAD65) PEPTIDE 207-220

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN	polymer	190	21623.1	1	UniProt (P04228) Pfam (PF00993) Pfam (PF07654) In PDB	Mus musculus (mouse)
2	B	65 KD GLUTAMIC ACID DECARBOXYLASE+H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN	polymer	221	25563.4	1	UniProt (Q05329) GenBank (387435) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (Q31135) In PDB	Homo sapiens (human)
3		water	water		18.0	76	Chemie (HOH)

Sequence modifications

A: 1 - 178 (UniProt: P04228)

PDB	External Database	Details
Ser 179	-	SEE REMARK 999
Ser 180	-	SEE REMARK 999
Ala 181	-	SEE REMARK 999
Asp 182	-	SEE REMARK 999
Leu 183	-	SEE REMARK 999
Val 184	-	SEE REMARK 999
Pro 185	-	SEE REMARK 999
Arg 186	-	SEE REMARK 999

B: 207 - 220 (UniProt: Q05329)

PDB	External Database	Details
Gly 201	-	SEE REMARK 999
Ser 202	-	SEE REMARK 999
His 203	-	SEE REMARK 999
Ser 204	-	SEE REMARK 999
Arg 205	-	SEE REMARK 999
Gly 206	-	SEE REMARK 999
Ser 189	-	SEE REMARK 999
Ser 190	-	SEE REMARK 999
Ala 191	-	SEE REMARK 999
Asp 192	-	SEE REMARK 999
Leu 193	-	SEE REMARK 999
Val 194	-	SEE REMARK 999
Pro 195	-	SEE REMARK 999
Arg 196	-	SEE REMARK 999

B: 1 - 188 (GenBank: 387435)

PDB	External Database	Details
Gly -5	-	SEE REMARK 999
Ser -4	-	SEE REMARK 999
Gly -3	-	SEE REMARK 999
Ser -2	-	SEE REMARK 999
Gly -1	-	SEE REMARK 999
Ser 0	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47186.6
All*	Total formula weight	47186.6

*Water molecules are not included.