1EQB
X-RAY CRYSTAL STRUCTURE AT 2.7 ANGSTROMS RESOLUTION OF TERNARY COMPLEX BETWEEN THE Y65F MUTANT OF E-COLI SERINE HYDROXYMETHYLTRANSFERASE, GLYCINE AND 5-FORMYL TETRAHYDROFOLATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | SERINE HYDROXYMETHYLTRANSFERASE | polymer | 417 | 45356.5 | 4 | UniProt (P00477) Pfam (PF00464) UniProt (by SIFTS) (P0A825) In PDB | Escherichia coli | |
| 2 | A, B, C, D | GLYCINE | non-polymer | 75.1 | 4 | Chemie (GLY) | |||
| 3 | A, B, C, D | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 4 | Chemie (PLP) | |||
| 4 | A, B, C, D | N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid | non-polymer | 473.4 | 4 | Chemie (FFO) | |||
| 5 | water | water | 18.0 | 287 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 417 (UniProt: P00477)
| PDB | External Database | Details |
|---|---|---|
| Phe 65 | Tyr 65 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 181425.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3182.6 | |
| All* | Total formula weight | 184608.5 |
