1EEN
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-D-A-D-BPA-PTYR-L-I-P-Q-Q-G
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN TYROSINE PHOSPHATASE 1B | polymer | 321 | 37349.6 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | PTP1B |
| 2 | B (B) | ALA-ASP-PBF-PTR-LEU-ILE-PRO | polymer | 7 | 1022.0 | 1 | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E (A) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Ser 215 | Cys 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38371.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 144.4 | |
| All* | Total formula weight | 38516.0 |
