1EE4
CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | KARYOPHERIN ALPHA | polymer | 423 | 46870.5 | 2 | UniProt (Q02821) Pfam (PF00514) Pfam (PF16186) In PDB | Saccharomyces cerevisiae (baker's yeast) | SERINE-RICH RNA POLYMERASE I SUPPRESSOR PROTEIN |
| 2 | C, D, E, F | MYC PROTO-ONCOGENE PROTEIN | polymer | 9 | 1000.2 | 4 | UniProt (P01106) In PDB | Homo sapiens (human) | |
| 3 | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A, B: 87 - 509 (UniProt: Q02821)
| PDB | External Database | Details |
|---|---|---|
| Asp 397 | Tyr 397 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 97741.9 | |
| All* | Total formula weight | 97741.9 |
