1E9Y
Crystal structure of Helicobacter pylori urease in complex with acetohydroxamic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UREASE SUBUNIT ALPHA | polymer | 238 | 26571.7 | 1 | UniProt (P14916) Pfam (PF00547) Pfam (PF00699) | HELICOBACTER PYLORI | UREA AMIDOHYDROLASE SUBUNIT ALPHA |
| 2 | B (B) | UREASE SUBUNIT BETA | polymer | 569 | 61761.4 | 1 | UniProt (P69996) Pfam (PF00449) Pfam (PF01979) | HELICOBACTER PYLORI | UREA AMIDOHYDROLASE SUBUNIT BETA |
| 3 | C (B) | ACETOHYDROXAMIC ACID | non-polymer | 75.1 | 1 | Chemie (HAE) | |||
| 4 | D, E (B) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 1 - 238 (UniProt: P14916)
B: 1 - 569 (UniProt: P69996)
| PDB | External Database | Details |
|---|---|---|
| Ala 170 | Ser 170 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Kcx 219 | Lys 219 | modified residue |
| Lys 324 | Leu 324 | conflict |
| Ala 355 | Ile 355 | conflict |
| Val 522 | Ile 522 | conflict |
| Asn 531 | Asp 531 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88333.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 192.5 | |
| All* | Total formula weight | 88525.6 |
