Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009039 | molecular_function | urease activity |
| A | 0016151 | molecular_function | nickel cation binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0035550 | cellular_component | urease complex |
| A | 0043419 | biological_process | urea catabolic process |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0009039 | molecular_function | urease activity |
| B | 0016151 | molecular_function | nickel cation binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| B | 0043419 | biological_process | urea catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE HAE B 800 |
| Chain | Residue |
| B | ALA169 |
| B | NI3002 |
| B | KCX219 |
| B | HIS221 |
| B | HIS248 |
| B | HIS274 |
| B | GLY279 |
| B | ASP362 |
| B | ALA365 |
| B | NI3001 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI B 3001 |
| Chain | Residue |
| B | KCX219 |
| B | HIS248 |
| B | HIS274 |
| B | GLY279 |
| B | HAE800 |
| B | NI3002 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI B 3002 |
| Chain | Residue |
| B | HIS136 |
| B | HIS138 |
| B | KCX219 |
| B | ASP362 |
| B | HAE800 |
| B | NI3001 |
Functional Information from PROSITE/UniProt
| site_id | PS01120 |
| Number of Residues | 14 |
| Details | UREASE_1 Urease nickel ligands signature. TAGGIDtHIHfisP |
| Chain | Residue | Details |
| B | THR129-PRO142 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 101 |
| Details | Region: {"description":"Urease gamma"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 135 |
| Details | Region: {"description":"Urease beta"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"via carbamate group"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01953","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11373617","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1kra |
| Chain | Residue | Details |
| B | HIS221 | |
| B | ARG338 | |
| B | ASP223 | |
| B | HIS322 | |
