1E9N

A second divalent metal ion in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1, and its implications for the catalytic mechanism

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE	polymer	318	35606.5	2	UniProt (P27695) Pfam (PF03372) In PDB	HOMO SAPIENS (HUMAN)	AP ENDONUCLEASE 1, HAP1, REF1, APE1
2	A, B	LEAD (II) ION	non-polymer		207.2	4	Chemie (PB)
3		water	water		18.0	349	Chemie (HOH)

Sequence modifications

A, B: 1 - 1 (PDB: 1E9N)
A, B: 2 - 318 (UniProt: P27695)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71213.0
Non-Polymers*	Number of molecules	4
	Total formula weight	828.8
All*	Total formula weight	72041.8

*Water molecules are not included.