1E8Y
Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | polymer | 966 | 110756.2 | 1 | UniProt (P48736) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | HOMO SAPIENS (HUMAN) | PTDINS-3-KINASE P110, PI3K |
| 2 | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A: 143 - 1102 (UniProt: P48736)
A: 1103 - 1108 (PDB: 1E8Y)
| PDB | External Database | Details |
|---|---|---|
| Met 143 | Pro 142 | cloning artifact |
| Ala 505 | Arg 505 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 110756.2 | |
| All* | Total formula weight | 110756.2 |
