1E8X
STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING
Replaces: 1QMMEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | polymer | 961 | 109952.6 | 1 | UniProt (O02697) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | SUS SCROFA (WILD BOAR) | PTDINS-3-KINASE P110, PI3K |
| 2 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 3 | A | LUTETIUM (III) ION | non-polymer | 175.0 | 9 | Chemie (LU) | |||
| 4 | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence modifications
A: 142 - 1094 (UniProt: O02697)
| PDB | External Database | Details |
|---|---|---|
| Ala 142 | - | expression tag |
| Ala 143 | - | expression tag |
| Ala 505 | Arg 505 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 109952.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2081.9 | |
| All* | Total formula weight | 112034.4 |
