1E42

Beta2-adaptin appendage domain, from clathrin adaptor AP2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	AP-2 COMPLEX SUBUNIT BETA	polymer	258	29088.5	2	UniProt (P63010) Pfam (PF02883) Pfam (PF09066)	HOMO SAPIENS (HUMAN)	PLASMA MEMBRANE ADAPTOR HA2/AP2 ADAPTIN BETA SUBUNIT, CLATHRIN ASSEMBLY PROTEIN COMPLEX 2 BETA LARGE CHAIN, AP105B, BETA2-ADAPTIN, ADAPTER-RELATED PROTEIN COMPLEX 2 BETA SUBUNIT, ADAPTOR PROTEIN COMPLEX AP-2 SUBUNIT BETA
2	C, H (A, B)	DITHIANE DIOL	non-polymer		152.2	2	Chemie (DTD)
3	D, I, J, K (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	E, F, M, N (A, B)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
5	G, O (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	L (B)	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
7	P, Q (A, B)	water	water		18.0	822	Chemie (HOH)

Sequence modifications

A, B: 701 - 937 (UniProt: P63010)

PDB	External Database	Details
Met 680	-	expression tag
Gly 681	-	expression tag
Ser 682	-	expression tag
Ser 683	-	expression tag
His 684	-	expression tag
His 685	-	expression tag
His 686	-	expression tag
His 687	-	expression tag
His 688	-	expression tag
His 689	-	expression tag
Ser 690	-	expression tag
Ser 691	-	expression tag
Gly 692	-	expression tag
Leu 693	-	expression tag
Val 694	-	expression tag
Pro 695	-	expression tag
Arg 696	-	expression tag
Gly 697	-	expression tag
Ser 698	-	expression tag
His 699	-	expression tag
Met 700	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58176.9
Non-Polymers*	Number of molecules	13
	Total formula weight	786.4
All*	Total formula weight	58963.3

*Water molecules are not included.