1E42
Beta2-adaptin appendage domain, from clathrin adaptor AP2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0030117 | cellular_component | membrane coat |
| A | 0030131 | cellular_component | clathrin adaptor complex |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0016192 | biological_process | vesicle-mediated transport |
| B | 0030117 | cellular_component | membrane coat |
| B | 0030131 | cellular_component | clathrin adaptor complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 971 |
| Chain | Residue |
| A | ALA754 |
| A | ILE755 |
| A | PRO769 |
| A | LEU770 |
| A | HOH2060 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 972 |
| Chain | Residue |
| A | PRO793 |
| A | VAL794 |
| B | GLN756 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 971 |
| Chain | Residue |
| B | ILE755 |
| B | PRO769 |
| B | LEU770 |
| B | ALA754 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 972 |
| Chain | Residue |
| A | GLN756 |
| B | PRO793 |
| B | VAL794 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 960 |
| Chain | Residue |
| A | ASN872 |
| A | HOH2198 |
| A | HOH2332 |
| A | HOH2337 |
| A | HOH2338 |
| A | HOH2340 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 960 |
| Chain | Residue |
| B | ASN872 |
| B | HOH2225 |
| B | HOH2351 |
| B | HOH2357 |
| B | HOH2358 |
| B | HOH2361 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 961 |
| Chain | Residue |
| B | GLU849 |
| B | HOH2253 |
| B | HOH2330 |
| B | HOH2331 |
| B | HOH2332 |
| B | HOH2389 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 962 |
| Chain | Residue |
| B | LYS842 |
| B | HOH2199 |
| B | HOH2315 |
| B | HOH2316 |
| B | HOH2317 |
| B | HOH2325 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI B 970 |
| Chain | Residue |
| A | HOH2096 |
| A | HOH2097 |
| A | HOH2148 |
| B | HIS735 |
| B | HOH2043 |
| B | HOH2049 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DTD A 950 |
| Chain | Residue |
| A | ALA746 |
| A | LEU747 |
| A | GLN748 |
| A | ARG834 |
| A | ARG879 |
| A | TYR888 |
| A | HOH2067 |
| A | HOH2402 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DTD B 950 |
| Chain | Residue |
| B | ALA746 |
| B | LEU747 |
| B | GLN748 |
| B | ARG834 |
| B | ALA877 |
| B | ARG879 |
| B | TYR888 |
| B | HOH2092 |
| B | HOH2419 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 980 |
| Chain | Residue |
| A | SER761 |
| A | PHE762 |
| A | ASN895 |
| A | ILE897 |
| A | GLU922 |
| A | VAL923 |
| A | HOH2119 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 980 |
| Chain | Residue |
| B | SER761 |
| B | ASN895 |
| B | ILE897 |
| B | GLU922 |
| B | VAL923 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 192 |
| Details | Region: {"description":"Interaction with ARRB1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by SRC","evidences":[{"source":"PubMed","id":"17456551","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18938240","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P62944","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
