1E2G
Human thymidylate kinase complexed with ADP, TDP and a magnesium-ion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYMIDYLATE KINASE | polymer | 215 | 24052.5 | 1 | UniProt (P23919) Pfam (PF02223) | HOMO SAPIENS (HUMAN) | TMPK |
| 2 | B (A) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) PubChem (18531120) PubChem (20711568) PubChem (1139) PubChem (23657880) PubChem (24802545) PubChem (44361457) PubChem (25113134) PubChem (51397487) PubChem (444919) PubChem (9700) PubChem (5274091) PubChem (5748250) PubChem (10147784) PubChem (129069890) PubChem (133126478) PubChem (164603144) | |||
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D (A) | THYMIDINE-5'-DIPHOSPHATE | non-polymer | 402.2 | 1 | Chemie (TYD) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | G (A) | water | water | 18.0 | 269 | Chemie (HOH) |
Sequence modifications
A: 1 - 212 (UniProt: P23919)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 200 | Arg 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24052.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1200.2 | |
| All* | Total formula weight | 25252.7 |
