1E2G
Human thymidylate kinase complexed with ADP, TDP and a magnesium-ion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYMIDYLATE KINASE | polymer | 215 | 24052.5 | 1 | UniProt (P23919) Pfam (PF02223) | HOMO SAPIENS (HUMAN) | TMPK |
| 2 | B (A) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) | |||
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D (A) | THYMIDINE-5'-DIPHOSPHATE | non-polymer | 402.2 | 1 | Chemie (TYD) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | G (A) | water | water | 18.0 | 269 | Chemie (HOH) |
Sequence modifications
A: 1 - 212 (UniProt: P23919)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 200 | Arg 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24052.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1200.2 | |
| All* | Total formula weight | 25252.7 |
