1DWQ
Crystal Structure of Hydroxynitrile Lyase from Manihot esculenta in Complex with Substrates Acetone and Chloroacetone:Implications for the Mechanism of Cyanogenesis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HYDROXYNITRILE LYASE | polymer | 262 | 29891.3 | 2 | UniProt (P52705) Pfam (PF00561) | MANIHOT ESCULENTA (CASSAVA) | (S)-ACETONE-CYANOHYDRIN LYASE, (S)-HYDROXYNITRILASE |
| 2 | C (A) | CHLOROACETONE | non-polymer | 92.5 | 1 | Chemie (ATO) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A, B: -4 - 1 (PDB: 1DWQ)
A, B: 2 - 258 (UniProt: P52705)
| PDB | External Database | Details |
|---|---|---|
| Pro -4 | - | cloning artifact |
| Ile -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Lys -1 | - | cloning artifact |
| Met 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59782.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.5 | |
| All* | Total formula weight | 59875.1 |
