1DVM
ACTIVE FORM OF HUMAN PAI-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | PLASMINOGEN ACTIVATOR INHIBITOR-1 | polymer | 379 | 42795.1 | 4 | UniProt (P05121) Pfam (PF00079) | Homo sapiens (human) | |
| 2 | E, F, G, H (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 1636 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 379 (UniProt: P05121)
| PDB | External Database | Details |
|---|---|---|
| His 150 | Asn 173 | engineered mutation |
| Thr 154 | Lys 177 | engineered mutation |
| Leu 319 | Gln 342 | engineered mutation |
| Ile 354 | Met 377 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 171180.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 141.8 | |
| All* | Total formula weight | 171322.1 |
