1DH3
CRYSTAL STRUCTURE OF A CREB BZIP-CRE COMPLEX REVEALS THE BASIS FOR CREB FAIMLY SELECTIVE DIMERIZATION AND DNA BINDING
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, D) | DNA (5'-D(*CP*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3') | polymer | 21 | 6424.1 | 2 | |||
| 2 | C, D (A, C) | TRANSCRIPTION FACTOR CREB | polymer | 55 | 6686.8 | 2 | UniProt (Q01147) Pfam (PF00170) | Mus musculus (house mouse) | |
| 3 | E (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | F, G, H, I (B, D, A, C) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A, C: 285 - 339 (UniProt: Q01147)
| PDB | External Database | Details |
|---|---|---|
| Ser 300 | Cys 216 | engineered mutation |
| Ser 310 | Cys 226 | engineered mutation |
| Ser 300 | Cys 253 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 26222.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 26246.3 |
