1DG5
DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND TRIMETHOPRIM
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | DIHYDROFOLATE REDUCTASE | polymer | 159 | 17661.0 | 1 | UniProt (P0A546) Pfam (PF00186) UniProt (by SIFTS) (P9WNX1) | Mycobacterium tuberculosis | DHFR |
2 | B (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
3 | C (A) | TRIMETHOPRIM | non-polymer | 290.3 | 1 | Chemie (TOP) | |||
4 | D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | G (A) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 17661.0 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1312.0 | |
All* | Total formula weight | 18973.0 |