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1D3H

HUMAN DIHYDROOROTATE DEHYDROGENASE COMPLEXED WITH ANTIPROLIFERATIVE AGENT A771726

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DIHYDROOROTATE DEHYDROGENASEpolymer36739856.51UniProt (Q02127)
Pfam (PF01180)
Homo sapiens (human)
2B
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3C
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
4D
(A)
(2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamidenon-polymer270.21Chemie (A26)
5E
(A)
FLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
6F
(A)
OROTIC ACIDnon-polymer156.11Chemie (ORO)
7G
(A)
waterwater18.0298Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39856.5
Non-Polymers*Number of molecules5
Total formula weight1037.8
All*Total formula weight40894.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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